LEAN (5-Amino-1MQ)
$119.00
Ships from Australia Discreet packaging
| Number of Items | Discount |
|---|---|
| 2 | 5% |
| 3 | 10% |
| 4 | 15% |
| 5 | 20% |
LEAN (5-amino-1MQ) – Advanced Metabolic Support for Fat Loss, Energy, and Body Recomposition
LEAN (5-amino-1MQ) is an advanced research compound designed to support metabolic efficiency, fat utilisation, and lean body composition. It has gained attention among researchers exploring body recomposition, non-stimulant fat loss support, and cellular energy pathways linked to energy balance.
Rather than relying on stimulant-driven effects, LEAN (5-amino-1MQ) is researched for its interaction with metabolic enzyme activity. This makes it particularly relevant for protocols focused on fat reduction, metabolic support, and the preservation of lean tissue during calorie deficit or recomposition-focused research.
For researchers seeking a non-hormonal compound that may support a leaner, more defined physique, LEAN (5-amino-1MQ) offers a distinct mechanism of action compared with traditional fat loss or performance-support compounds.
How LEAN (5-amino-1MQ) Works
LEAN (5-amino-1MQ) functions by inhibiting nicotinamide N-methyltransferase (NNMT), an enzyme involved in metabolism, energy regulation, and fat tissue activity. NNMT is closely associated with nicotinamide metabolism and has been studied for its role in obesity, insulin resistance, and altered metabolic function.
By reducing NNMT activity, LEAN (5-amino-1MQ) may help support higher availability of nicotinamide adenine dinucleotide (NAD+), a key cofactor involved in cellular energy production, mitochondrial function, and metabolic signalling. NAD+ availability is also linked to SIRT1 activity, a pathway involved in metabolic regulation and cellular function.
Through these pathways, LEAN (5-amino-1MQ) is researched for its potential to support fat utilisation, metabolic output, and lean tissue preservation. This mechanism makes it especially interesting in body recomposition research, where the goal is often to reduce fat mass while maintaining performance and lean muscle.
Key Benefits of LEAN (5-amino-1MQ)
Supports Fat Metabolism – Researched for its role in pathways linked to fat utilisation, energy balance, and body composition.Promotes Lean Body Composition – May assist with preserving lean mass while supporting fat reduction during recomposition-focused protocols.Enhances Metabolic Efficiency – Targets NNMT, a metabolic enzyme closely linked to fat tissue activity and energy regulation.Supports NAD+ Production – May help increase NAD+ availability, a key factor in cellular energy metabolism and mitochondrial function.Activates SIRT1 Pathways – Associated with broader metabolic regulation, cellular repair signalling, and energy homeostasis.Non-Stimulant Mechanism – Offers a distinct alternative to stimulant-based fat loss compounds and hormonal performance enhancers.Useful for Recomposition Research – Well suited to protocols focused on improving body composition while maintaining lean tissue and training output.
Why Choose LEAN (5-amino-1MQ)?
LEAN (5-amino-1MQ) is a compelling option for researchers investigating compounds aimed at fat loss, metabolic support, and body recomposition. Its mechanism is tied to NNMT inhibition rather than hormonal or stimulant-driven pathways, making it particularly interesting in advanced metabolic research settings.
Because it is researched for its influence on NAD+, SIRT1, and metabolic efficiency, LEAN (5-amino-1MQ) may be especially useful where the intended goal is to support fat loss while maintaining lean tissue and energy output. This gives it a clear place in cutting, recomposition, and metabolic support protocols.
For those exploring compounds that may support a leaner physique while maintaining muscle and supporting metabolic pathways, LEAN (5-amino-1MQ) stands out as a valuable addition to a research protocol.
Take your research to the next level with LEAN (5-amino-1MQ) – an advanced compound for metabolic support, fat utilisation, and lean body composition.
Recommended Combinations
For researchers looking to maximise results, LEAN (5-amino-1MQ) can be effectively stacked with other compounds depending on the intended goal:
- For Cutting: Stack with SHRED (GW-0742) or MELT (SR-9011) to further support endurance, fat metabolism, and lean tissue retention during calorie deficit protocols.
- For Recomposition: Pair with MAINTAIN (MK-2866) to support lean muscle preservation while pursuing a harder, leaner physique.
- For Recovery & Performance Support: Combine with GROWTH (MK-677) where recovery, training output, and overall body composition support are also being explored.
Dosage
- Concentration: 50mg/mL
- Volume: 30mL
- A typical dosage is 50mg daily, though dosages up to 100mg daily are sometimes used in research settings.
- Each bottle provides a 30-day supply at the suggested dosage.
Storage
Store in a cool, dark place, such as a cupboard or pantry, away from direct sunlight and heat. Keep sealed when not in use to help maintain product stability.
Ingredients / Purity Report
- Active Ingredient: LEAN (5-Amino-1-methylquinolinium)
- Other Ingredients: Food-grade USP glycol, food-grade ethyl alcohol, and essential oils.
- For the latest HPLC purity report, please email sales@auslabs.email.
Medical References
- Neelakantan, H., Vance, V., Wetzel, M. D., Wang, H. L., McHardy, S. F., Finnerty, C. C., Hommel, J. D., & Watowich, S. J. (2018). Selective and membrane-permeable small molecule inhibitors of nicotinamide N-methyltransferase reverse high fat diet-induced obesity in mice. Biochemical Pharmacology, vol. 147, pp. 141–152.
- Dimet-Wiley, A., Wu, Q., Wiley, J. T. et al. (2022). Reduced calorie diet combined with NNMT inhibition establishes a distinct microbiome in DIO mice. Scientific Reports, vol. 12, article 484.
- Liu, J.-R., Deng, Z.-H., Zhu, X.-J., Zeng, Y.-R., Guan, X.-X., & Li, J.-H. (2021). Roles of Nicotinamide N-Methyltransferase in Obesity and Type 2 Diabetes. BioMed Research International, 2021, Article ID 9924314.
Disclaimer
No statements on this page have been evaluated by the Therapeutic Goods Administration (TGA). This product is not intended to diagnose, treat, cure, or prevent any disease or illness. LEAN (5-amino-1MQ) is strictly for research purposes only. Please refer to the TERMS OF USE for more information.
